Abstract
The perioperative period may have long-term consequences on cognitive function in the elderly patient. In this special article, we summarize the rationale and evidence that the anesthetic per se is a contributor. The evidence at this point is considered suggestive and further research is needed, especially in humans.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Aged
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Alzheimer Disease / chemically induced
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Alzheimer Disease / pathology
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Anesthesia / adverse effects
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Anesthetics, Inhalation / adverse effects*
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Animals
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Brain / drug effects*
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Cognition Disorders / chemically induced
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Cognition Disorders / etiology
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Dementia / chemically induced*
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Dementia / etiology
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Humans
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Neurofibrillary Tangles / drug effects