Determination of complication rate of PICC lines in oncological patients

J Pak Med Assoc. 2009 Oct;59(10):663-7.

Abstract

Objective: To determine the complication rate of (PICCs) peripherally inserted central catheters in cancer patients with a 1 year prospective cohort study.

Methods: All PICCs inserted in adult cancer patients in Radiology Department of The Aga Khan University Hospital were followed prospectively till removed or patient expired and pattern of complications noted.

Results: One hundred and fourty six PICCs were inserted over a period of 1 year and followed for a total of 3329 catheter-days; median placement, 14 days: range 3-218 days. Of these 67 (32.8%) PICCs were complicated and removed earlier, for a rate of 14.4/1000 PICC-days. Patients with haematologic malignancies were more likely to have complications as compared to those with solid tissue malignancies.

Conclusions: Despite a significant complication rate, PICCs are a relatively safe and cost effective method of establishing central venous access.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents / administration & dosage
  • Catheterization, Central Venous / adverse effects*
  • Catheterization, Peripheral / adverse effects*
  • Female
  • Humans
  • Infusions, Intravenous / instrumentation
  • Male
  • Middle Aged
  • Neoplasms / drug therapy
  • Pakistan / epidemiology
  • Prospective Studies
  • Radiography, Interventional
  • Risk Factors

Substances

  • Antineoplastic Agents