Four new fatty acid esters from the Feces of Trogopterus xanthipes

Lipids. 2009 Sep;44(9):849-53. doi: 10.1007/s11745-009-3329-z. Epub 2009 Aug 1.

Abstract

Four new fatty acid esters have been isolated from Feces Trogopterus. Their structures were determined by spectroscopic and chemical methods to be bis(7-hydroxyheptyl) icosanedioate (1), bis(7-hydroxyheptyl) heptadecanedioate (2), bis(7-hydroxyheptyl) decanedioate (3), and bis(7-hydroxyheptyl) octanedioate (4). In the anticoagulative assay, compounds 3 and 4 had significant antithrombin activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anticoagulants / analysis*
  • Anticoagulants / isolation & purification
  • Anticoagulants / pharmacology*
  • Drugs, Chinese Herbal / analysis
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / pharmacology
  • Fatty Acids / analysis*
  • Fatty Acids / isolation & purification
  • Fatty Acids / pharmacology*
  • Feces / chemistry*
  • Molecular Structure
  • Rabbits
  • Sciuridae / metabolism*
  • Thrombin / antagonists & inhibitors
  • Thrombin / metabolism

Substances

  • Anticoagulants
  • Drugs, Chinese Herbal
  • Fatty Acids
  • Thrombin