Evaluation of a new rapid antigen test using immunochromatography for detection of human metapneumovirus in comparison with real-time PCR assay

J Clin Microbiol. 2009 Sep;47(9):2981-4. doi: 10.1128/JCM.00321-09. Epub 2009 Jul 1.

Abstract

A new rapid human metapneumovirus (hMPV) detection kit using immunochromatography (SAS hMPV test) was compared to real-time PCR for 224 nasal swab specimens, 96.4% of which were obtained from children of <15 years of age. The overall sensitivity and specificity were 82.3% and 93.8%, respectively, suggesting that this test is useful for pediatricians to diagnose hMPV infection in a clinical setting.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antigens, Viral / analysis*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunoassay / methods*
  • Infant
  • Infant, Newborn
  • Male
  • Metapneumovirus / isolation & purification*
  • Nasal Mucosa / virology
  • Paramyxoviridae Infections / diagnosis*
  • Polymerase Chain Reaction / methods
  • Sensitivity and Specificity

Substances

  • Antigens, Viral