[Characteristics of clinical presentation, diagnosis, and surgical treatment of temporal partial epilepsy]

Zh Vopr Neirokhir Im N N Burdenko. 2009 Apr-Jun:(2):29-34; discussion 35.
[Article in Russian]

Abstract

Results of surgical treatment of 55 patients with pharmacologically resistant temporal epilepsy (age 16-43 years) admitted to Polenov Neurosurgical Institute (Saint-Petersburg, Russia) were assessed. EEG-monitoring as the part of examination protocol discovered stable focus of paroxysmal activity in frontotemporal area in 30 patients (54.5%). It is shown that the evaluated multifocal type is characterized by specific clinical, neurophysiological and neuroradiological features. Results of complex examination substantiated appropriateness of distinguishing of this type and possibility of its relevant and timely evaluation for optimization of surgical treatment. Semeiology of paroxysmal clinical symptoms, being in direct correlation with data obtained by EEG-monitoring which indicated frontotemporal localization of epileptogenic focus, shows the dynamics of pathological process in the late stages of temporal epileptogenesis. Discovered clinical and neurophysiological features determined optimal tactics of surgical management of frontotemporal type of partial epilepsy - open surgical resection of the anterior 2/3 of temporal lobe combined with subpial resection of frontal cortex with addition subpial cortical transsections with continuous intraoperative electrophysiological monitoring.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Anterior Temporal Lobectomy / methods*
  • Brain Mapping
  • Epilepsy, Temporal Lobe / diagnosis*
  • Epilepsy, Temporal Lobe / etiology
  • Epilepsy, Temporal Lobe / surgery*
  • Female
  • Humans
  • Male
  • Treatment Outcome
  • Young Adult