[Characteristics of supposedly bacterial community acute pneumonia among HIV-positive patients: prospective preliminary study]

Rev Pneumol Clin. 2009 Jun;65(3):137-42. doi: 10.1016/j.pneumo.2009.03.004. Epub 2009 May 7.
[Article in French]

Abstract

Introduction: Community-acquired pneumonia (CAP) is the second leading cause of hospitalization in the respirology department in Abidjan after tuberculosis. Frequently associated with HIV infection, it has a high mortality rate of about 20% to 30%. The aim of this study is to identify the specificities and severity factors associated with bacterial CAP (BCAP) outcome in HIV-positive patients.

Methods: The authors conducted a prospective and comparative preliminary study on two groups of patients: 29 HIV-positive patients with BCAP and 21 HIV-negative patients with BCAP. All of the patients were hospitalized for BCAP with symptoms of severity according to the usual score of severity.

Results: The sociodemographic, clinical and paraclinical characteristics were similar in both groups. Failures and deaths were more frequent in the group with HIV infection. In particular, HIV infected patients with a body mass index under 18.5 and a rate of T CD4 lymphocytes lower than 200/mm(3) presented the least favourable evolution.

Conclusions: A more extensive study should help define the appropriate severity criteria for BCAP associated with HIV infection.

Publication types

  • English Abstract

MeSH terms

  • AIDS-Related Opportunistic Infections / drug therapy
  • AIDS-Related Opportunistic Infections / mortality*
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Body Mass Index
  • CD4 Lymphocyte Count
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / mortality
  • Female
  • HIV Infections / mortality*
  • Humans
  • Male
  • Pneumonia / drug therapy
  • Pneumonia / mortality*
  • Prospective Studies
  • Severity of Illness Index

Substances

  • Anti-Bacterial Agents