Identification of a novel allele HLA-DRB1*0478 by sequence-based typing in a Chinese individual

Tissue Antigens. 2009 Jun;73(6):625-7. doi: 10.1111/j.1399-0039.2009.01246.x. Epub 2009 Apr 6.

Abstract

A novel allele HLA-DRB1*0478 is described. This variant has one nucleotide substitution in exon 2. This mutations result in an amino acid substitution at condon 70 (CAG --> CGG) from Gln to Arg.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Amino Acid Substitution / genetics*
  • Asian People / genetics
  • Base Sequence
  • China
  • Exons / genetics
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Humans
  • Molecular Sequence Data
  • Sequence Alignment

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains