Abstract
We describe a previously healthy patient with chronic otitis media complicated with cerebellar abscess caused by Tsukamurella tyrosinosolvens. The organism was identified based on conventional biochemical identification methods, PCR-restriction fragment length polymorphism analysis of the hsp65 gene, and 16S rRNA gene sequencing. The patient was treated successfully with debridements and prolonged antibiotic therapy.
MeSH terms
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Actinomycetales / isolation & purification*
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Actinomycetales Infections / diagnosis*
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Actinomycetales Infections / microbiology
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Adult
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Anti-Bacterial Agents / therapeutic use
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Bacterial Proteins / genetics
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Bacterial Typing Techniques
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Brain Abscess / drug therapy
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Brain Abscess / microbiology*
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Brain Abscess / surgery
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DNA Fingerprinting
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DNA, Bacterial / genetics
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DNA, Ribosomal / genetics
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Female
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Heat-Shock Proteins / genetics
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Humans
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Otitis Media / complications
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Polymorphism, Restriction Fragment Length
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RNA, Ribosomal, 16S / genetics
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Sequence Analysis, DNA
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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DNA, Bacterial
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DNA, Ribosomal
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Heat-Shock Proteins
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RNA, Ribosomal, 16S