Age-related changes in the human lens. Clinical assessment of age-related changes in the human lens

Acta Ophthalmol (Copenh). 1991 Jun;69(3):310-4. doi: 10.1111/j.1755-3768.1991.tb04820.x.

Abstract

We compared two methods for assessing changes in the human lens associated with age. The first is a subjective method for quantifying light absorption by the lens. It is useful for determining the functional effect of age-related increases in lens density, especially for short-wavelength light. The second method objectively and rapidly measures the increase in scattered light with increasing lens density. These two methods accurately measured age-related changes and were highly correlated with each other (r = 0.72, P less than 0.001). Both methods were evaluated in a population of normal eyes, eyes with ocular hypertension, and eyes with primary open angle glaucoma. We found ni significant differences among these groups with either method.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aging / physiology*
  • Cataract / physiopathology
  • Glaucoma, Open-Angle / physiopathology
  • Humans
  • Lens, Crystalline / physiopathology*
  • Middle Aged
  • Ocular Hypertension / physiopathology
  • Photic Stimulation
  • Random Allocation
  • Reproducibility of Results
  • Vision Tests / methods