Evaluation on quality of life and analysis on its correlation with TCM syndromes in patients of chronic hepatitis B

Chin J Integr Med. 2009 Feb;15(1):30-3. doi: 10.1007/s11655-009-0030-z. Epub 2009 Mar 7.

Abstract

Objective: To evaluate the quality of life (QOL) in patients with chronic hepatitis B (CHB) and analyze its correlation with traditional Chinese medicine (TCM) syndrome types.

Methods: With cross-sectional investigation adopted, the QOL of 335 CHB patients was studied by the World Health Organization Quality of Life BREF Questionnaire (WHOQOL-BREF) and the chronic liver disease questionnaire (CLDQ). The results was compared with that of 30 healthy persons.

Results: The QOL of the patients with chronic hepatitis B was lower than the healthy persons with signififi cant difference between them (P<0.01). Also it was different in patients of different TCM syndrome types (P<0.05 or P<0.01). The lowest QOL was shown in patients of the blood-stasis blocking vessel type and Gan ()-stagnation with Pi ()-defificiency type (P<0.01).

Conclusion: The QOL of CHB patients is lower than of healthy persons and closely correlated with TCM syndrome types.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Case-Control Studies
  • Health
  • Hepatitis B, Chronic / pathology*
  • Humans
  • Medicine, Chinese Traditional*
  • Quality of Life*
  • Surveys and Questionnaires
  • Syndrome
  • World Health Organization