Treatment of early Parkinson's disease. Part 1

Eur Neurol. 2009;61(4):193-205. doi: 10.1159/000197103. Epub 2009 Jan 29.

Abstract

The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-part article reviews motor symptom efficacy data for the newest PD treatment options, as well as for established therapies. Safety and tolerability data are also reviewed. Part 2 of the article reviews key findings relevant to the assessment of potential neuroprotective therapies and the treatment of non-motor symptoms.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiparkinson Agents / therapeutic use*
  • Clinical Trials as Topic
  • Dopamine Agonists / adverse effects
  • Dopamine Agonists / therapeutic use
  • Humans
  • Levodopa / therapeutic use
  • Monoamine Oxidase Inhibitors / therapeutic use
  • Movement Disorders / drug therapy*
  • Parkinson Disease / drug therapy*
  • Patient Compliance

Substances

  • Antiparkinson Agents
  • Dopamine Agonists
  • Monoamine Oxidase Inhibitors
  • Levodopa