[A case of submucosal invasive cancer of the sigmoid colon, recurring as multiple liver metastases one year after the surgery]

Gan To Kagaku Ryoho. 2008 Nov;35(12):2144-6.
[Article in Japanese]

Abstract

A 55-year-old woman underwent colonoscopy due to a positive fecal occult blood test during a mass screening examination, and a 0-Ip type early cancer in the sigmoid colon was found. Endoscopic mucosal resection was performed for this lesion. Histological examination of the endoscopic resected specimen showed a well-differentiated adenocarcinoma invading submucosal layer (depth of invasion, 6,000 microm), positive lymph vessel invasion, and cut end negative. The patient was referred to our hospital, and an additional sigmoidectomy with lymphadenectomy was conducted. Histological examination revealed no residual cancer and no lymph node metastasis. One year after the surgery, an abdominal CT scan showed liver metastases in the segment 4 and 7. The patient underwent a medial segmentectomy and partial resection of the segment 7 of the liver. After the surgery, 8 courses of oral UFT/LV therapy as adjuvant chemotherapy were administered. The patient remains free of recurrence 2 years and 7 months after the first surgery.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Colonoscopy
  • Combined Modality Therapy
  • Female
  • Humans
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / surgery
  • Middle Aged
  • Neoplasm Invasiveness / pathology
  • Recurrence
  • Sigmoid Neoplasms / drug therapy
  • Sigmoid Neoplasms / pathology*
  • Sigmoid Neoplasms / surgery
  • Time Factors
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents