From molecular shape to potent bioactive agents I: bioisosteric replacement of molecular fragments

ChemMedChem. 2009 Jan;4(1):41-4. doi: 10.1002/cmdc.200800313.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • COS Cells
  • Cells, Cultured
  • Chlorocebus aethiops
  • Computer Simulation
  • Drug Design
  • Inhibitory Concentration 50
  • PPAR alpha / agonists*
  • PPAR alpha / chemistry*
  • PPAR gamma / agonists*
  • PPAR gamma / chemistry*
  • Propionates / chemistry*
  • Propionates / pharmacology
  • Software*
  • Structure-Activity Relationship

Substances

  • PPAR alpha
  • PPAR gamma
  • Propionates