A novel allele, HLA-A*0128, identified by sequence-based typing in a Chinese individual

Tissue Antigens. 2008 Dec;72(6):599-600. doi: 10.1111/j.1399-0039.2008.01128.x. Epub 2008 Oct 17.

Abstract

In this report, we describe the identification of a novel allele HLA-A*0128, which was found in a registered donor from China Marrow Donor Program. The A*0128 allele differs from the A*0113 by one nucleotide substitutions in exon 2 at position 282 (G-->C). The mutation results in a codon change: at codon 70 where a glutamine acid is substituted by a histidine acid.

MeSH terms

  • Alleles*
  • Base Sequence
  • China
  • Exons / genetics
  • HLA-A Antigens / genetics*
  • Humans
  • Molecular Sequence Data
  • Mutation / genetics

Substances

  • HLA-A Antigens