Ratiometric multimodal chemosensors based on cubic silsesquioxanes for monitoring solvent polarity

Kazuo Tanaka; Kenichi Inafuku; Yoshiki Chujo

doi:10.1016/j.bmc.2008.10.016

Ratiometric multimodal chemosensors based on cubic silsesquioxanes for monitoring solvent polarity

Bioorg Med Chem. 2008 Dec 1;16(23):10029-33. doi: 10.1016/j.bmc.2008.10.016. Epub 2008 Oct 11.

Authors

Kazuo Tanaka¹, Kenichi Inafuku, Yoshiki Chujo

Affiliation

¹ Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

PMID: 18954994
DOI: 10.1016/j.bmc.2008.10.016

Abstract

We report the multi-functionalized cubic silsesquioxane (POSS) as the ratiometric multimodal chemosensors for monitoring solvent polarity with fluorescence and (19)F NMR. The alteration of the dispersion state of the modified POSS by changing solvent polarity can be reflected into the orthogonal signal responses for the fluorescence and (19)F NMR. In addition, the ratiometric dual monitoring for the enzymatic reaction was performed using the POSS-based chemosensor.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fluorescent Dyes / chemistry*
Models, Chemical
Organosilicon Compounds / chemistry*
Solvents / chemistry*
Spectrometry, Fluorescence

Substances

Fluorescent Dyes
Organosilicon Compounds
Solvents