One of the topics of most concern for nephrologists today is how to reduce the mortality of our patients and we try to have markers to help us know which patients are at greatest risk. Cardiovascular disease is one of the main causes of morbidity and mortality in patients with chronic kidney disease. Oxidative stress, inflammation and endothelial dysfunction have been recognized as nontraditional cardiovascular risk factors, but they are achieving growing importance. On the other hand, quality management systems are being applied on an increasing basis in routine clinical practice, demonstrating that the way of working in the center may be a key factor in the results obtained.