[The effects of statins on the cerebral haemodynamics measured by transcranial Doppler in ischemic stroke patients]

Zhonghua Nei Ke Za Zhi. 2008 Apr;47(4):288-90.
[Article in Chinese]

Abstract

Objective: To evaluate the effects of statins on the cerebral haemodynamics of ischemic stroke patients with transcranial Doppler (TCD).

Methods: 70 inpatients with acute ischemic stroke were divided into two groups according whether they had taken statins after stroke. The change of the cerebral haemodynamics was studied in the two groups with TCD three months after stroke.

Results: Three months later, the systolic flow velocities and mean flow velocities of bilateral middle cerebral arteries in the statins groups significantly increased (P <0.05). The pulse index of bilateral middle cerebral arteries in statins group significantly decreased (P <0.05). The flow velocities and pulse index of bilateral middle cerebral arteries in control group don't change significantly (P > 0.05).

Conclusions: Statins may have the effects of improving the situation of cerebral haemodynamics of patients with ischemic stroke.

MeSH terms

  • Aged
  • Blood Flow Velocity
  • Brain Ischemia / diagnostic imaging*
  • Brain Ischemia / drug therapy*
  • Brain Ischemia / physiopathology
  • Cerebrovascular Circulation
  • Female
  • Humans
  • Hypolipidemic Agents / therapeutic use*
  • Male
  • Middle Aged
  • Prospective Studies
  • Ultrasonography, Doppler, Transcranial / methods*

Substances

  • Hypolipidemic Agents