Cardiogenic shock with stunned myocardium during triple-H therapy treated with intra-aortic balloon pump counterpulsation

Neurocrit Care. 2009;10(1):76-82. doi: 10.1007/s12028-008-9135-2. Epub 2008 Sep 23.

Abstract

Introduction: Excessive use of adrenergic agents may result in stunned myocardium.

Cases: We report the cases of two patients with subarachnoid hemorrhage (SAH) complicated by cardiogenic shock secondary to triple-H therapy for cerebral vasospasm. Both patients had normal cardiac function on admission and no signs of acute myocardial infarction at the onset of cardiogenic shock. Intra-aortic balloon pump (IABP) counterpulsation was used to maintain adequate cerebral perfusion while enabling the high doses of norepinephrine that were being administered to be reduced. Reversal of the myocardial dysfunction after vasopressors were discontinued supported a diagnosis of catecholamine-induced stunned myocardium.

Conclusion: IABP counterpulsation may be one therapeutic option for patients with vasospasm after SAH when high doses of vasopressors can induce severe myocardial dysfunction. However, this invasive device may not be sufficient to maintain adequate cerebral perfusion and fatal embolic events can complicate the clinical course.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Intra-Aortic Balloon Pumping*
  • Middle Aged
  • Myocardial Stunning / chemically induced
  • Myocardial Stunning / diagnosis
  • Myocardial Stunning / therapy*
  • Norepinephrine / adverse effects*
  • Shock, Cardiogenic / chemically induced
  • Shock, Cardiogenic / diagnosis
  • Shock, Cardiogenic / therapy*
  • Subarachnoid Hemorrhage / complications
  • Subarachnoid Hemorrhage / therapy
  • Vasoconstrictor Agents / adverse effects*
  • Vasospasm, Intracranial / etiology
  • Vasospasm, Intracranial / therapy

Substances

  • Vasoconstrictor Agents
  • Norepinephrine