Neonatal sepsis caused by a CTX-M-32-producing Escherichia coli isolate

J Med Microbiol. 2008 Oct;57(Pt 10):1303-1305. doi: 10.1099/jmm.0.2008/000729-0.

Abstract

We describe what we believe to be the first case of neonatal sepsis caused by CTX-M-producing Escherichia coli, in a low-weight preterm infant, born to a colonized mother who had received antibiotic treatment antepartum. Increased dissemination of extended-spectrum beta-lactamase-producing E. coli in the community should be borne in mind for empirical therapy of sepsis in high-risk newborns.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Escherichia coli / enzymology*
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Infections / transmission
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases / microbiology*
  • Infectious Disease Transmission, Vertical
  • Male
  • Meropenem
  • Pregnancy
  • Pregnancy Complications, Infectious / microbiology
  • Sepsis / microbiology*
  • Thienamycins / therapeutic use
  • beta-Lactamases / metabolism*

Substances

  • Anti-Bacterial Agents
  • Thienamycins
  • beta-Lactamases
  • beta-lactamase CTX-M-32, E coli
  • Meropenem