Functional consequences of schizophrenia are important. According to this, prevention has been developed using various approaches. The strategy based on the neuro-developmental hypothesis of the illness is not useful at the time. Identification of ultra high risk groups is an interesting way to develop possibilities of intervention which goal is to reduce the possibility of transition to psychosis in those samples. But the lack of specificity of the definition of those groups, make this strategy difficult to use in general population. Increasing the permeability of the different filters along the pathway to mental health care can be more promising in general population. By now, prevention strategies have to be improved in the filed of schizophrenia, and make the proof of ther interest beyond the research perspectives.