Highly sensitive and quantitative detection of BCR-ABL kinase domain mutations by ligation PCR

Leukemia. 2008 Dec;22(12):2288-91. doi: 10.1038/leu.2008.180. Epub 2008 Jul 10.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fusion Proteins, bcr-abl / chemistry
  • Fusion Proteins, bcr-abl / genetics*
  • Genetic Testing / methods*
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*
  • Mutation
  • Polymerase Chain Reaction / methods*
  • Protein Structure, Tertiary
  • Sensitivity and Specificity

Substances

  • Fusion Proteins, bcr-abl