This study assessed the relationship between anemia in infancy and the social reproduction profile of the families. It was conducted with a representative sample of 254 children of the city of Itupeva, SP. Hemoglobin < 11 g/dL, determined by portable hemoglobin analyzer, was used to define anemia. Profiles of social reproduction had been built by 2 groups of indicators: working and living conditions. Three social homogeneous groups had been defined: upper, intermediate, lower. Anemia was prevalent in 41.7%, and more frequent in lower social groups (13.2%; 40.6%; 46.2%), but with no significant difference (p>0.05). However, profile of social reproduction of anemic families showed significant difference (p<0.05). Occurrence of anemia was related to poor working conditions in lower social groups and consequently inappropriate living conditions.