Ion transport inhibition in the medullary thick ascending limb of Henle's loop by cytochrome P450-arachidonic acid metabolites

Adv Prostaglandin Thromboxane Leukot Res. 1991:21A:209-12.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Arachidonic Acid
  • Arachidonic Acids / metabolism*
  • Arachidonic Acids / pharmacology
  • Cells, Cultured
  • Cytochrome P-450 CYP2J2
  • Cytochrome P-450 Enzyme System / metabolism*
  • Depression, Chemical
  • Furosemide / pharmacology
  • Ion Channel Gating / drug effects*
  • Loop of Henle / drug effects*
  • Loop of Henle / metabolism
  • Ouabain / pharmacology
  • Oxygen Consumption / drug effects
  • Oxygenases / metabolism*
  • Rabbits
  • Rubidium / metabolism
  • Sodium-Potassium-Exchanging ATPase / antagonists & inhibitors

Substances

  • Arachidonic Acids
  • Arachidonic Acid
  • Ouabain
  • 20-carboxyarachidonic acid
  • Furosemide
  • Cytochrome P-450 Enzyme System
  • Oxygenases
  • Cytochrome P-450 CYP2J2
  • Sodium-Potassium-Exchanging ATPase
  • Rubidium