The inheritance of alcohol sensitivity and of patterns of alcohol use

Alcohol Alcohol Suppl. 1991:1:141-5.

Abstract

Compared to controls, sons of alcoholics have been reported to exhibit decreased sensitivity to a challenge dose of alcohol (e.g. a smaller increase in body-sway: Schuckit, 1985). We reanalyze alcohol challenge data from a general population sample of Australian twin pairs (Martin et al., 1985a, b). By fitting direction-of-causation models, we show that in males differences in body-sway are largely a consequence, not a cause, of differences in alcohol consumption patterns. In females, direction-of-causation could not be resolved.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Alcohol Drinking*
  • Alcoholic Intoxication / genetics
  • Alcoholic Intoxication / physiopathology*
  • Alcoholism / genetics*
  • Analysis of Variance
  • Australia
  • Ethanol / toxicity*
  • Family
  • Female
  • Humans
  • Male
  • Motor Activity*
  • Sex Factors
  • Surveys and Questionnaires
  • Twins, Dizygotic
  • Twins, Monozygotic

Substances

  • Ethanol