Serological response against Mycobacterium avium complex glycolipid antigens in patients with acquired immunodeficiency syndrome

Yugo Ashino; Heinner Guio; Aikichi Iwamoto; Ikuya Yano; Takeshi Matsumura; Toshio Hattori

doi:10.1111/j.1348-0421.2008.00003.x

Serological response against Mycobacterium avium complex glycolipid antigens in patients with acquired immunodeficiency syndrome

Microbiol Immunol. 2008 Jan;52(1):36-9. doi: 10.1111/j.1348-0421.2008.00003.x.

Authors

Yugo Ashino¹, Heinner Guio, Aikichi Iwamoto, Ikuya Yano, Takeshi Matsumura, Toshio Hattori

Affiliation

¹ Division of Infectious and Respiratory Diseases, School of Medicine, Post Graduate Division, Tohoku University; Japan.

PMID: 18352911
DOI: 10.1111/j.1348-0421.2008.00003.x

Abstract

In 43 MAC infected patients (23 non-HIV and 20 AIDS) the IgG response against 3 BCG and 2 MAC antigens was assessed. The response to four antigens in patients with AIDS was considerably lower than in non-HIV infected patients. Therefore, antibody production against MAC glycolipid antigens was impaired in AIDS patients.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Acquired Immunodeficiency Syndrome / complications*
Adult
Aged
Antibodies, Bacterial / blood*
Antigens, Bacterial / immunology*
Female
Glycolipids / immunology*
Humans
Immunoglobulin G / blood
Male
Middle Aged
Mycobacterium avium Complex / immunology*
Mycobacterium bovis / immunology

Substances

Antibodies, Bacterial
Antigens, Bacterial
Glycolipids
Immunoglobulin G