Postoperative anemia and quality of life after primary hip arthroplasty in patients over 65 years old

Anesth Analg. 2008 Apr;106(4):1056-61, table of contents. doi: 10.1213/ane.0b013e318164f114.

Abstract

Background: It is uncertain whether anemia in elderly patients after primary hip arthroplasty has an effect on their quality of life.

Methods: We conducted a prospective observational study over 3 mo to investigate the association between discharge hemoglobin levels and subjective experience of quality of life at 2 mo postoperatively in patients aged over 65 yr who were scheduled for primary hip arthroplasty. Quality of life was measured preoperatively and at 2 mo postoperatively using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the Functional Assessment of Cancer Therapy Anemia (FACT-Anemia) subscale. Pearson correlation coefficients between change in SF-36 and FACT-Anemia subscale scores (from preoperatively to 2 mo postoperatively) and hemoglobin on Day 8 were calculated.

Results: Eighty-seven patients were included in the study. Data were available at 2 mo postoperatively from 79 of these patients. The correlation between Day 8 postoperative hemoglobin and change in SF-36 was 0.49 (P < 0.0005) and change in FACT-Anemia subscale score was 0.46 (P = < 0.0005). The correlation was not significantly changed after adjusting for advancing age, presence of significant cardiovascular disease, or whether the patient was transfused.

Conclusions: We found a positive correlation between hemoglobin levels on discharge and change in quality of life scores from preoperatively to 2 mo postoperatively in patients over 65 yr old after primary hip arthroplasty.

MeSH terms

  • Aged
  • Anemia / blood
  • Anemia / epidemiology*
  • Anemia / physiopathology*
  • Anemia / psychology
  • Arthroplasty, Replacement, Hip / adverse effects*
  • Blood Transfusion
  • Female
  • Health Surveys
  • Hemoglobins / metabolism*
  • Humans
  • Male
  • Prospective Studies
  • Quality of Life*
  • Social Behavior
  • Surveys and Questionnaires

Substances

  • Hemoglobins