Laparoscopy and intersex: report of 5 cases of male pseudohermaphroditism

J Med Invest. 2008 Feb;55(1-2):147-50. doi: 10.2152/jmi.55.147.

Abstract

From May, 1999 to August, 2006, we performed laparoscopic diagnosis and treatment for 103 cases of impalpable testes. Among those we found 5 cases of male pseudohermaphroditism of different etiologies. Three males presented by impalpable testes with ambiguous genitalia and 2 females presented by primary amenorrhea. All of them have 46-XY normal male chromosomal pattern. In the first 3 cases, the etiology was complete gonadal dysgenesis, and 2 cases with persistent Mullerian syndrome. Timed gonadectomy for the first case and laparoscopic orchiopexy for the other 2 cases were performed. For the other 2 female cases, the etiology was complete androgen insensitivity syndrome and laparoscopic bilateral orchiectomy was performed for both of them. All the procedures were done without complications with satisfactory results.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Androgen-Insensitivity Syndrome / complications
  • Child
  • Child, Preschool
  • Constriction, Pathologic / complications
  • Disorders of Sex Development / diagnosis
  • Disorders of Sex Development / etiology
  • Disorders of Sex Development / genetics
  • Disorders of Sex Development / surgery*
  • Female
  • Gonadal Dysgenesis / complications
  • Gonads / surgery
  • Humans
  • Laparoscopy
  • Male
  • Mullerian Ducts / pathology
  • Treatment Outcome