What is healthcare-associated pneumonia and how is it managed?

Curr Opin Infect Dis. 2008 Apr;21(2):168-73. doi: 10.1097/QCO.0b013e3282f4f248.

Abstract

Purpose of review: Pneumonia developing before hospital admission in patients in close contact with the health system was recently termed 'healthcare-associated pneumonia' and proposed as a new category of respiratory infection. We focus on the recent literature concerning the epidemiology, causative organisms, antibiotic susceptibilities, and outcomes of and empirical antibiotic therapy for this condition.

Recent findings: The reported incidence of healthcare-associated pneumonia among patients requiring hospitalization for pneumonia ranges from 17% to 67%. Hospitalization within 90 days before pneumonia, attending a dialysis clinic and residing in a nursing home were the most common criteria for healthcare-associated pneumonia. Compared with patients with community-acquired pneumonia, those with healthcare-associated pneumonia are older, have greater co-morbidity, and are more likely to have aspiration pneumonia and pneumonia caused by antibiotic-resistant pathogens. Patients with healthcare-associated pneumonia also more frequently initially receive an inappropriate antibiotic therapy, have higher case fatality rates and have longer hospital stay.

Summary: Many patients hospitalized with pneumonia via the emergency department have healthcare-associated pneumonia. There are significant differences in the spectrum of causative organisms and antibiotic susceptibilities between healthcare-associated and community-acquired pneumonia. Physicians should differentiate patients with healthcare-associated pneumonia from those with community-acquired pneumonia to promote a targeted approach when selecting initial antibiotic therapy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Cross Infection* / drug therapy
  • Cross Infection* / epidemiology
  • Cross Infection* / microbiology
  • Gram-Negative Bacteria
  • Gram-Positive Bacteria
  • Humans
  • Incidence
  • Nursing Homes
  • Pneumonia, Bacterial* / drug therapy
  • Pneumonia, Bacterial* / epidemiology
  • Pneumonia, Bacterial* / microbiology
  • Renal Dialysis
  • Risk Factors

Substances

  • Anti-Bacterial Agents