Acquired zinc deficiency acrodermatitis associated with nephrotic syndrome

Pediatr Dermatol. 2008 Jan-Feb;25(1):56-9. doi: 10.1111/j.1525-1470.2007.00583.x.

Abstract

We present a child with new-onset nephrotic syndrome, acrodermatitis, low serum zinc levels and decreased serum alkaline phosphatase. A diagnosis of acquired zinc deficiency acrodermatitis was made. Oral zinc supplementation led to rapid clinical resolution. The etiology of zinc deficiency in nephrotic syndrome remains unknown.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acrodermatitis / diagnosis
  • Acrodermatitis / drug therapy
  • Acrodermatitis / pathology*
  • Alkaline Phosphatase / blood*
  • Biopsy, Needle
  • Child
  • Deficiency Diseases / complications
  • Deficiency Diseases / diagnosis*
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Leg Dermatoses / diagnosis
  • Leg Dermatoses / drug therapy
  • Male
  • Nephrotic Syndrome / complications
  • Nephrotic Syndrome / diagnosis*
  • Severity of Illness Index
  • Treatment Outcome
  • Zinc / blood
  • Zinc / deficiency*
  • Zinc / therapeutic use

Substances

  • Alkaline Phosphatase
  • Zinc