The molecular pathology of amyloid deposition in Alzheimer's disease

Mol Neurobiol. 1991;5(2-4):389-98. doi: 10.1007/BF02935560.

Authors

R N Martins¹, P J Robinson, J O Chleboun, K Beyreuther, C L Masters

Affiliation

¹ University Department of Surgery, Repatriation General Hospital, Hollywood, Perth, Western Australia.

PMID: 1823142
DOI: 10.1007/BF02935560

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Adult
Aged
Alzheimer Disease / genetics
Alzheimer Disease / metabolism*
Amino Acid Sequence
Amyloid / metabolism*
Amyloid Precursor Protein Secretases
Amyloid beta-Peptides / biosynthesis*
Amyloid beta-Protein Precursor / genetics
Amyloid beta-Protein Precursor / metabolism*
Amyloid beta-Protein Precursor / physiology
Aspartic Acid Endopeptidases
Cerebral Amyloid Angiopathy / genetics
Cerebral Amyloid Angiopathy / metabolism
DNA Mutational Analysis
Endopeptidases / metabolism
Gene Expression
Humans
Middle Aged
Models, Biological
Molecular Sequence Data
Neurofibrillary Tangles / metabolism
Protein Processing, Post-Translational

Substances

Amyloid
Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Amyloid Precursor Protein Secretases
Endopeptidases
Aspartic Acid Endopeptidases
BACE1 protein, human