Dissemination of CTX-M-15 beta-lactamase genes carried on Inc FI and FII plasmids among clinical isolates of Escherichia coli in a university hospital in Istanbul, Turkey

J Clin Microbiol. 2008 Mar;46(3):1110-2. doi: 10.1128/JCM.01974-07. Epub 2008 Jan 9.

Abstract

The CTX-M-1 group was found in 86.8% of the Escherichia coli isolates from Istanbul. A subset study revealed all isolates carrying bla(CTX-M-15) genes flanked by the insertion element ISEcp1. Plasmid typing of transconjugates carrying bla(CTX-M-15) showed that most isolates belonged to the Inc/rep FII group but that one isolate also belonged to the FI group.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Cefotaxime / pharmacology
  • Ceftazidime / pharmacology
  • Conjugation, Genetic*
  • Escherichia coli / drug effects
  • Escherichia coli / enzymology*
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology
  • Escherichia coli Proteins / genetics
  • F Factor / genetics*
  • Hospitals, University*
  • Humans
  • Microbial Sensitivity Tests
  • Plasmids / genetics*
  • Polymerase Chain Reaction
  • Prevalence
  • Random Amplified Polymorphic DNA Technique
  • Turkey / epidemiology
  • beta-Lactam Resistance
  • beta-Lactamases / genetics*

Substances

  • Anti-Bacterial Agents
  • Escherichia coli Proteins
  • Ceftazidime
  • beta-lactamase CTX-M-15
  • beta-Lactamases
  • Cefotaxime