Comments on "Blockade of angiogenesis by small molecule antagonists to protease-activated receptor-1: association with endothelial cell growth suppression and induction of apoptosis"

J Pharmacol Exp Ther. 2008 Jan;324(1):404-5; author reply 406-7. doi: 10.1124/jpet.107.131847.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Angiogenesis Inhibitors / pharmacology*
  • Animals
  • Apoptosis / drug effects
  • Cell Line
  • Cell Proliferation / drug effects
  • Chick Embryo
  • Endothelial Cells / cytology
  • Endothelial Cells / drug effects*
  • Endothelial Cells / physiology
  • Humans
  • Indazoles / pharmacology*
  • Neovascularization, Physiologic / drug effects
  • Pyrroles / pharmacology*
  • Quinazolines / pharmacology*
  • Receptor, PAR-1 / antagonists & inhibitors*
  • Receptor, PAR-1 / physiology
  • Urea / analogs & derivatives*
  • Urea / pharmacology

Substances

  • Angiogenesis Inhibitors
  • Indazoles
  • N3-cyclopropyl-7-((4-(1-methylethyl)phenyl)methyl)-7H-pyrrolo(3, 2-f)quinazoline-1,3-diamine
  • Pyrroles
  • Quinazolines
  • RWJ-56110
  • Receptor, PAR-1
  • Urea