Resolution and sensitivity aspects of ultrafast J-resolved 2D NMR spectra

J Magn Reson. 2008 Feb;190(2):339-45. doi: 10.1016/j.jmr.2007.11.019. Epub 2007 Dec 4.

Abstract

Recent ultrafast techniques enable nD NMR spectra to be obtained in a single scan. However, resolution enhancement in the ultrafast domain leads to important sensitivity losses and lineshape distortions. In order to understand better resolution and spatial encoding aspects of continuous phase-encoding schemes, a theoretical and experimental comparison of different excitation patterns is carried out. Molecular diffusion appears to be the main cause of signal-to-noise ratio decrease, and a multi-echo excitation scheme is proposed to limit its effects when a good resolution is needed. Results obtained on 2D J-resolved spectra are presented.

MeSH terms

  • Magnetic Resonance Spectroscopy / methods*
  • Propionates / chemistry
  • Sensitivity and Specificity
  • Temperature

Substances

  • Propionates
  • 3-bromopropionic acid