Potential underdetection of pT(3a) renal-cell carcinoma with laparoscopic morcellation

J Endourol. 2007 Oct;21(10):1183-6. doi: 10.1089/end.2007.9910.

Abstract

Background and purpose: After tumor morcellation, staging relies on clinical imaging. Our goal was to determine the size distribution of stage pT(3a) renal-cell carcinomas (RCCs) and whether evidence of extrarenal invasion is present on preoperative imaging.

Patients and methods: We selected patients with organ-confined RCC treated surgically from 1975 to 2002 and subsequently found to have stage pT(3a) disease. Preoperative radiologic imaging reports were reviewed for evidence of extrarenal tumor extension.

Results: Of the 1781 patients treated surgically for pM(0) RCC, 129 (7.2%) had pT(3a) disease. Tumor size distributions were: 17 (13.2%) < or =4 cm, 38 (29.5%) >4 cm but < or =7 cm, and 74 (57.4%) >7cm. There were 6 patients (4.7%) with extrarenal extension according to preoperative imaging. Of these, 2 (5.3%) had tumors >4 cm but < or =7cm, and 4 (5.4%) had tumors >7 cm.

Conclusion: Many pT(3a) tumors are small, and the majority is understaged clinically. Thus, morcellation in these patients would prevent accurate staging.

MeSH terms

  • Aged
  • Carcinoma, Renal Cell / classification
  • Carcinoma, Renal Cell / diagnosis*
  • Carcinoma, Renal Cell / diagnostic imaging*
  • Carcinoma, Renal Cell / pathology
  • Female
  • Humans
  • Kidney Neoplasms / classification
  • Kidney Neoplasms / diagnosis*
  • Kidney Neoplasms / diagnostic imaging*
  • Kidney Neoplasms / pathology
  • Laparoscopy / methods
  • Male
  • Middle Aged
  • Radiography
  • Sensitivity and Specificity