[Identification of a new Puumala hantavirus subtype in rodents from China]

Bing Du Xue Bao. 2007 Jul;23(4):320-5.
[Article in Chinese]

Abstract

In order to detect the nucleic acid of Puumala hantavirus, RNA was extracted from lungs of bank voles captured in Northeast China, and partial S and M genome segments of Puumala virus were amplified by RT-PCR and sequenced. Phylogenetic analysis suggested that Chinese Puumala virus had diverged from the common node of PUUV, with accumulating nucleotide substitutions and formed a distinct lineage from other Puumala viruses. Newly found Puumala virus was most closely related to the Kamiiso-8Cr-95 and Tobetsu-60Cr-93 strains which came from Japan and the muju strains which came from South Korea. By analysis of S and M genome segments of Puumala virus, we deduced a new Puumala virus subtype did exist in Northeast China.

MeSH terms

  • Animals
  • Base Sequence
  • China
  • Chlorocebus aethiops
  • Evolution, Molecular
  • Genome, Viral
  • Molecular Sequence Data
  • Orthohantavirus / genetics
  • Phylogeny
  • Puumala virus / classification
  • Puumala virus / genetics*
  • Puumala virus / isolation & purification
  • Reverse Transcriptase Polymerase Chain Reaction
  • Rodentia / virology*
  • Sequence Analysis, DNA
  • Vero Cells

Associated data

  • GENBANK/EF211819
  • GENBANK/EF211820
  • GENBANK/EF211821
  • GENBANK/EF211822
  • GENBANK/EF211823
  • GENBANK/EF211824
  • GENBANK/EF211825