Non-invasive evaluation of coronary vasospasm using a combined hyperventilation and cold-pressure-test perfusion CMR protocol

J Cardiovasc Magn Reson. 2007;9(5):759-64. doi: 10.1080/10976640701544662.

Abstract

Coronary vasospasm is a severe vasoconstriction of an epicardial coronary artery, which may lead to myocardial ischemia and cause symptoms of angina. The gold-standard for diagnosing coronary vasospasm is to perform an intracoronary provocation test and to demonstrate the epicardial vasoconstriction by coronary angiography. We report the case of a patient with coronary vasospasm in whom we succeeded to non-invasively provoke and subsequently non-invasively demonstrate myocardial ischemia by perfusion cardiovascular magnetic resonance (CMR).

Publication types

  • Case Reports

MeSH terms

  • Acetylcholine
  • Acute Coronary Syndrome / drug therapy
  • Acute Coronary Syndrome / etiology*
  • Acute Coronary Syndrome / pathology
  • Acute Coronary Syndrome / physiopathology
  • Adult
  • Cardiac Catheterization
  • Cold Temperature*
  • Coronary Angiography
  • Coronary Vasospasm / complications
  • Coronary Vasospasm / diagnosis*
  • Coronary Vasospasm / drug therapy
  • Coronary Vasospasm / physiopathology
  • Coronary Vessels / pathology
  • Coronary Vessels / physiopathology*
  • Electrocardiography
  • Humans
  • Hyperventilation*
  • Magnetic Resonance Imaging, Cine / methods*
  • Male
  • Predictive Value of Tests
  • Pressure*
  • Severity of Illness Index
  • Vasoconstriction*
  • Vasodilator Agents / therapeutic use

Substances

  • Vasodilator Agents
  • Acetylcholine