Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors

Angew Chem Int Ed Engl. 2007;46(42):7960-4. doi: 10.1002/anie.200703198.

Authors

Arturo J Vegas¹, James E Bradner, Weiping Tang, Olivia M McPherson, Edward F Greenberg, Angela N Koehler, Stuart L Schreiber

Affiliation

¹ Howard Hughes Medical Institute, Chemistry and Chemical Biology, Harvard University, Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA 02142, USA.

No abstract available

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Cell Line
Enzyme Inhibitors / chemistry*
Histone Deacetylase Inhibitors*
Humans
Hydrocarbons, Fluorinated / chemistry*
Microarray Analysis / instrumentation
Microarray Analysis / methods*
Molecular Structure
Stereoisomerism

Substances

Enzyme Inhibitors
Histone Deacetylase Inhibitors
Hydrocarbons, Fluorinated

Grants and funding