Dynamic decomposition/recombination of hydrogen bonds in molecular duplex strands

Yong Yang; Jun-Feng Xiang; Chuan-Feng Chen

doi:10.1021/ol701868w

Dynamic decomposition/recombination of hydrogen bonds in molecular duplex strands

Org Lett. 2007 Oct 11;9(21):4355-7. doi: 10.1021/ol701868w. Epub 2007 Sep 13.

Authors

Yong Yang¹, Jun-Feng Xiang, Chuan-Feng Chen

Affiliation

¹ Beijing National Laboratory for Molecular Sciences, Center for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China.

PMID: 17850158
DOI: 10.1021/ol701868w

Abstract

Dynamic decomposition/recombination of hydrogen bonds in the hydrazide based molecular duplex strands was explored by variable-temperature 1H NMR experiments. A shuttle-like dynamic process of the two constituent molecules of the duplex strands between two degenerate states was observed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA / chemistry*
Hydrogen Bonding
Magnetic Resonance Spectroscopy
Models, Molecular*
Molecular Structure
Thermodynamics

Substances

DNA