The lack of endothelization after drug-eluting stent implantation as a cause of fatal late stent thrombosis

Jozef Jakabcin; Marian Bystron; Radim Spacek; Josef Veselka; Martin Kvasnak; Petr Kala; Jaroslav Malý; Pavel Cervinka

doi:10.1007/s11239-007-0080-2

The lack of endothelization after drug-eluting stent implantation as a cause of fatal late stent thrombosis

J Thromb Thrombolysis. 2008 Oct;26(2):154-8. doi: 10.1007/s11239-007-0080-2. Epub 2007 Aug 29.

Authors

Jozef Jakabcin¹, Marian Bystron, Radim Spacek, Josef Veselka, Martin Kvasnak, Petr Kala, Jaroslav Malý, Pavel Cervinka

Affiliation

¹ Department of Cardiology, Masaryk hospital Usti nad Labem, Socialni pece 3316/12A, 401 13, Usti nad Labem, Czech Republic. jozef.jakabcin@mnul.cz

PMID: 17764000
DOI: 10.1007/s11239-007-0080-2

Abstract

The authors present a fatal case of late thrombosis of paclitaxel-eluting stent implanted in the left main stem occurring 6 months after the procedure and 3 weeks after the cessation of clopidogrel. An autopsy has shown the lack of endothelization of deployed stent.

Publication types

Case Reports

MeSH terms

Angioplasty, Balloon, Coronary / adverse effects
Angioplasty, Balloon, Coronary / instrumentation*
Autopsy
Cardiovascular Agents / administration & dosage*
Clopidogrel
Coronary Angiography
Drug-Eluting Stents*
Endothelial Cells / pathology*
Fatal Outcome
Humans
Male
Middle Aged
Myocardial Infarction / diagnostic imaging
Myocardial Infarction / therapy*
Paclitaxel / administration & dosage*
Platelet Aggregation Inhibitors / therapeutic use
Prosthesis Design
Thrombosis / etiology*
Thrombosis / pathology
Ticlopidine / analogs & derivatives
Ticlopidine / therapeutic use
Treatment Outcome

Substances

Cardiovascular Agents
Platelet Aggregation Inhibitors
Clopidogrel
Ticlopidine
Paclitaxel