An Economic and Practical Synthesis of the 2-Tetrahydrofuranyl Ether Protective Group

Tetrahedron Lett. 2006 Jul 17;47(29):5111-5113. doi: 10.1016/j.tetlet.2006.05.081.

Abstract

Primary, secondary, and tertiary alcohols as well as phenols and carbohydrates are efficiently transformed into the corresponding 2-tetrahydrofuranyl ethers by a combination of Mn(0) powder and CCl(4) in tetrahydrofuran.