Background: Palmar fasciitis associated with polyarthralgia is a rare paraneoplastic syndrome, frequently observed in women, and in most cases associated with ovarian carcinoma.
Case report: A 51 year-old man complained of extensive palmar dermatological lesions associated with polyarthralgia of the legs. A few months earlier, cholangiocarcinoma had been diagnosed due to cholestatic icterus. The cutaneous biopsy confirmed the diagnosis of palmar fasciitis associated with polyarthralgia.
Discussion: This paraneoplastic syndrome is rarely described in digestive carcinoma and never in cholangiocarcinoma. The diagnosis is clinical, confirmed by certain laboratory exams. The evolution is similar to that of the carcinoma. Only curative treatment can achieve regression of the symptoms.