Abstract
Clinical isolates of Acinetobacter baumannii (n = 470) were collected during a 7-year period and investigated for the genetic determinants of resistance to expanded-spectrum beta-lactams. Thirty-one isolates produced the TEM-92 extended-spectrum beta-lactamase (ESBL) and were clonally related. This is the first report of A. baumannii producing a TEM-type ESBL.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter Infections* / epidemiology
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Acinetobacter Infections* / microbiology
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Acinetobacter Infections* / transmission
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Acinetobacter baumannii / classification
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Acinetobacter baumannii / drug effects
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Acinetobacter baumannii / enzymology
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Acinetobacter baumannii / genetics*
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Anti-Bacterial Agents / pharmacology
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Cross Infection* / epidemiology
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Cross Infection* / microbiology
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Cross Infection* / transmission
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Humans
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Italy / epidemiology
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Microbial Sensitivity Tests
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beta-Lactam Resistance / genetics
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beta-Lactamases / biosynthesis*
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beta-Lactamases / chemistry
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beta-Lactamases / classification
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beta-Lactamases / genetics*
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beta-Lactams / pharmacology
Substances
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Anti-Bacterial Agents
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beta-Lactams
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beta-Lactamases