The goal of the paper is to refer to and to inform about our own experiences with the Sub-Tenon's anesthesia in the surgery of the anterior as well as posterior segment of the eye. In cataract surgery it is equally efficient as the retrobulbar, peribulbar or topic anesthesia, and it is safer because no sharp needle is used. We operate on the posterior segment in sub-Tenon's anesthesia in patients with contraindicated general anesthesia because of their advanced age, decompensated diabetes mellitus or hypertension, in whom the pars plana vitrectomy is the only possibility to improve the patients' vision. Using the sub-Tenon's anesthesia, about 13.000 cataract surgeries and 127 pars plana vitrectomies without complications were performed. The simple pars plana vitrectomy may be realized at the outpatient basis as well.