New Eremophilane Type Lactones from the Roots of Ligularia veitchiana

Z Jia; Y Zhao; R Tan

doi:10.1055/s-2006-961486

New Eremophilane Type Lactones from the Roots of Ligularia veitchiana

Planta Med. 1992 Aug;58(4):365-7. doi: 10.1055/s-2006-961486.

Authors

Z Jia¹, Y Zhao, R Tan

Affiliation

¹ State Key Laboratory of Applied Organic Chemistry at Lanzhou University. Lanzhou 730000, People's Republic of China.

PMID: 17226486
DOI: 10.1055/s-2006-961486

Abstract

Phytochemical investigation of the roots of LIGULARIA VEITCHIANA has resulted in the characterization of two new eremophilanolides together with beta-sitosterol, stigmasterol, taraxol, and liguhodgsonal whose structure was further confirmed by the (13)C-NMR techniques. The structures of the new constituents were elucidated by spectroscopic methods and shown to be 1beta, 10beta-epoxy-6beta(2'-hydroxymethylacryloyloxy)-8beta-hydroxy-eremophila-7(11)-en-12,8alpha-olide ( 1) and 1beta, 10beta-epoxy-6beta-(2'-hydroxymethylacryloyloxy)-8beta-ethoxy-eremophila-7(11)-en-12,8alpha-olide ( 2).