This study aimed to measurement of corneal astigmatism in non diabetic and diabetic patient with Keratometry. This perspective study was conducted at Nepal Medical College Teaching Hospital from March to June 2004 to find out clinical evaluation of corneal astigmatism in non diabetic and diabetic patients. A total 224 patients were include. Corneal astigmatism readings with the Takagi KM-1 Sutcliff type Keratometry was obtained by single examiners on 130 non diabetic patients (where as 112 right eye and 109 left eye) and 94 diabetic patients (both eyes) corneas. Corneal dioptric and magnitude of astigmatism were assessed. Average corneal diopters were 43.88 and 43.81 in non diabetic and diabetic cases. Average corneal astigmatism was 0.30 D and 0.07D in non diabetic and diabetic cases. Less astigmatism present on diabetic patient to compare non diabetic patients in total and both sex. Chances of diabetes mellitus are more visible in non astigmatism patient compare to astigmatism patients in both sexes (Table-1 and 2). No difference in astigmatic rule i.e. with the rule astigmatism in both diabetic and non diabetic patients but less astigmatism present in diabetic one.