Staphylococcal cassette chromosome mec and Panton-Valentine leukocidin characterization of methicillin-resistant Staphylococcus aureus clones

J Clin Microbiol. 2007 Mar;45(3):1019-21. doi: 10.1128/JCM.01706-06. Epub 2006 Dec 27.

Abstract

Staphylococcal cassette chromosome mec (SCCmec) types and Panton-Valentine leukocidin (PVL) gene carriage were compared among suspected community-associated methicillin-resistant Staphylococcus aureus MRSA (CA-MRSA) and health care-associated MRSA (HA-MRSA) isolates. CA-MRSA isolates carried the SCCmec type IV complex, and most were PVL positive. The HA-MRSA isolates carried the SCCmec type II complex and did not harbor the PVL genes.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Toxins / genetics*
  • Chromosomes, Bacterial / genetics*
  • Community-Acquired Infections / microbiology
  • Cross Infection / microbiology
  • Exotoxins / genetics*
  • Florida
  • Humans
  • Leukocidins / genetics*
  • Methicillin / pharmacology
  • Methicillin Resistance / genetics*
  • Microbial Sensitivity Tests
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus / classification*
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / genetics

Substances

  • Anti-Bacterial Agents
  • Bacterial Toxins
  • Exotoxins
  • Leukocidins
  • Panton-Valentine leukocidin
  • Methicillin