A recurrent in-frame insertion in a CEBPA transactivation domain is a polymorphism rather than a mutation that does not affect gene expression profiling-based clustering of AML

Blood. 2007 Jan 1;109(1):389-90. doi: 10.1182/blood-2006-08-042325.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • CCAAT-Enhancer-Binding Proteins / genetics*
  • CCAAT-Enhancer-Binding Proteins / physiology
  • Cluster Analysis
  • Cohort Studies
  • DNA Mutational Analysis
  • Gene Duplication
  • Gene Expression Profiling
  • Humans
  • Leukemia, Myeloid / epidemiology
  • Leukemia, Myeloid / genetics*
  • Mutagenesis, Insertional
  • Polymorphism, Genetic*
  • Protein Structure, Tertiary
  • Transcriptional Activation

Substances

  • CCAAT-Enhancer-Binding Proteins
  • CEBPA protein, human