Achiral, cheap, and potent inhibitors of Plasmepsins I, II, and IV

ChemMedChem. 2006 Dec;1(12):1341-5. doi: 10.1002/cmdc.200600223.
No abstract available

MeSH terms

  • Animals
  • Aspartic Acid Endopeptidases / antagonists & inhibitors*
  • Binding Sites
  • Crystallography, X-Ray
  • Models, Molecular
  • Molecular Structure
  • Plasmodium falciparum / enzymology*
  • Protease Inhibitors / chemical synthesis
  • Protease Inhibitors / chemistry
  • Protease Inhibitors / pharmacology*
  • Protozoan Proteins
  • Structure-Activity Relationship

Substances

  • Protease Inhibitors
  • Protozoan Proteins
  • Aspartic Acid Endopeptidases
  • plasmepsin
  • plasmepsin II