Disseminated Mycobacterium avium complex infection in an immunocompetent pregnant woman

BMC Infect Dis. 2006 Oct 22:6:154. doi: 10.1186/1471-2334-6-154.

Abstract

Background: Disseminated mycobacterium avium complex (MAC) occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity.

Case presentation: A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further work-up demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen.

Conclusion: This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Antitubercular Agents / therapeutic use
  • Female
  • Humans
  • Immunocompetence / immunology*
  • Lung Diseases / microbiology
  • Lung Diseases / pathology
  • Mycobacterium avium-intracellulare Infection* / diagnosis
  • Mycobacterium avium-intracellulare Infection* / drug therapy
  • Placenta / microbiology
  • Prednisone / therapeutic use
  • Pregnancy
  • Pregnancy Complications, Infectious / immunology*
  • Pregnancy Complications, Infectious / microbiology*

Substances

  • Anti-Inflammatory Agents
  • Antitubercular Agents
  • Prednisone