Influence of gender on outcomes after intra-arterial thrombolysis for acute ischemic stroke

Neurology. 2006 Jun 13;66(11):1745-6. doi: 10.1212/01.wnl.0000218208.31305.84.

Abstract

Recent data suggest that women obtain greater benefit than men from IV fibrinolysis for acute ischemic stroke. It is unknown whether this gender-thrombolysis advantage extends to those treated with intra-arterial (IA) thrombolysis. The authors evaluated the independent effect of gender among ischemic stroke patients treated with IA fibrinolysis and found no differences in short-term clinical and angiographic outcomes between men and women who received IA thrombolysis for acute ischemic stroke.

MeSH terms

  • Aged
  • Brain Ischemia / drug therapy*
  • Brain Ischemia / epidemiology*
  • Comorbidity
  • Female
  • Fibrinolytic Agents / administration & dosage*
  • Humans
  • Infusions, Intra-Arterial
  • Male
  • Outcome Assessment, Health Care / methods*
  • Prognosis
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Sex Factors
  • Stroke / drug therapy*
  • Stroke / epidemiology*
  • Thrombolytic Therapy / statistics & numerical data*
  • Tissue Plasminogen Activator / administration & dosage
  • Treatment Outcome
  • United States / epidemiology
  • Urokinase-Type Plasminogen Activator / administration & dosage

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator
  • Urokinase-Type Plasminogen Activator